Epidermolysis Bullosa, also colloquially known as butterfly skin disease, a rare genetic condition that makes your skin very fragile. While the symptoms usually show up in babies or young children, sometimes, the signs start showing later in life. The inherited condition can affect teenagers as well as adults. Currently, there is no cure for this disease, but there are treatment options that help to relieve the symptoms. Efforts can also be made to prevent complications like an infection.<\/p>\n
What is butterfly skin disease?<\/h2>\n
Butterfly skin disease or epidermolysis bullosa (EB) is an inherited disease of the connective tissues that affects the skin and makes it extremely fragile. \u201cJust by a minor friction or trauma to the skin can lead to blisters and skin tears,\u201d says dermatologist Dr Khushboo Jha<\/a>.<\/p>\n It makes the skin very delicate and fragile resembling a butterfly\u2019s wings. Apart from the skin, this disease affects the mucous membranes of the body. However, it can become severe, and affect the food pipe and the urinary bladder. Approximately 50 in 1 million live births are diagnosed with butterfly skin disease in the world, according to research published in the Medical Journal, Armed Forces India<\/a>.<\/p>\n The butterfly skin disease symptoms are quite variable, depending upon the type and its severity. But some of the more common symptoms include:<\/p>\n \u201cThe main cause behind this condition lies in genetic mutations in the genes that work to produce protein which functions to hold the skin layers\u2019 together. \u201cThe proteins that play a role in this include keratin, collagen VII, laminin and integrin. The inherited genetic mutation leads to either absence of such proteins or fault in them, and leads to easy blisters\u2019 development in the skin,\u201d explains the expert.<\/p>\n There are four major types of EB:<\/p>\n The life expectancy of people with this condition depends on the type and severity:<\/p>\n There is no definitive cure for butterfly skin disease, but there are treatment options:<\/p>\n Butterfly skin disease is genetic, so it cannot be prevented after birth. There is also no cure, but there are treatments that can help to manage symptoms and prevent infections.<\/p>\n Related FAQs<\/span><\/p>\n Yes, gene therapy is under development and showing promise. Notably, a topical gene therapy called Vyjuvek (beremagene geperpavec) was approved for Dystrophic epidermolysis bullosa (DEB) caused by mutations in the COL7A1 gene. It delivers working copies of the gene directly to wounds.<\/p>\n<\/div>\n<\/div>\n Yes, though EB typically manifests in infancy or early childhood, some milder forms can go undiagnosed until adulthood or persist into adult life. Mild one may cause lifelong blistering of hands and feet.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n","protected":false},"excerpt":{"rendered":" Ever wondered why you have fragile skin? It may be because you have the butterfly skin disease or epidermolysis bullosa, which is very rare. Epidermolysis Bullosa, also colloquially known as butterfly skin disease, a rare genetic condition that makes your skin very fragile. While the symptoms usually show up in babies or young children, sometimes, […]<\/p>\n","protected":false},"author":1,"featured_media":17702,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_gspb_post_css":"","fifu_image_url":"https:\/\/images.healthshots.com\/healthshots\/en\/uploads\/2025\/05\/02141938\/Butterfly1.jpg","fifu_image_alt":"","footnotes":""},"categories":[1],"tags":[],"offerexpiration":[],"class_list":["post-17701","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blogs"],"_links":{"self":[{"href":"https:\/\/luxelifestyletech.com\/index.php?rest_route=\/wp\/v2\/posts\/17701","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/luxelifestyletech.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/luxelifestyletech.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/luxelifestyletech.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/luxelifestyletech.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=17701"}],"version-history":[{"count":0,"href":"https:\/\/luxelifestyletech.com\/index.php?rest_route=\/wp\/v2\/posts\/17701\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/luxelifestyletech.com\/index.php?rest_route=\/wp\/v2\/media\/17702"}],"wp:attachment":[{"href":"https:\/\/luxelifestyletech.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=17701"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/luxelifestyletech.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=17701"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/luxelifestyletech.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=17701"},{"taxonomy":"offerexpiration","embeddable":true,"href":"https:\/\/luxelifestyletech.com\/index.php?rest_route=%2Fwp%2Fv2%2Fofferexpiration&post=17701"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}![\"Butterfly](\"https:\/\/images.healthshots.com\/healthshots\/en\/uploads\/2025\/05\/02141938\/Butterfly1.jpg\")
What are the symptoms of butterfly skin disease?<\/h2>\n
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What causes butterfly skin disease?<\/h2>\n
What are the types of butterfly skin disease?<\/h2>\n
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What is the life expectancy of people with butterfly skin disease?<\/h2>\n
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![\"A](\"https:\/\/images.healthshots.com\/healthshots\/en\/uploads\/2024\/01\/22111253\/suns-sensitvity.jpg\")
How to treat butterfly skin disease?<\/h2>\n
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Is there a gene therapy for butterfly skin disease?<\/h3>\n
Are adults affected by butterfly skin disease?<\/h3>\n